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HER2-Positive Breast Cancer, 1st Edition

Author :
By Sara Hurvitz, MD and Kelly McCann
Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates ...view more

Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.

ISBN :
9780323581226
Publication Date :
16-08-2018
Stock Status :
Please allow 10-14 working days for delivery
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Get a quick, expert overview of clinically-focused topics and guidelines that are relevant to testing for HER2, which contributes to approximately 25% of breast cancers today. This concise resource by Drs. Sara Hurvitz, and Kelly McCann consolidates today’s available information on this growing topic into one convenient resource, making it an ideal, easy-to-digest reference for practicing and trainee oncologists.


Key Features
  • Covers the diagnosis, treatments and targeted therapies, and management of breast cancers that are HER2-positive.
  • Contains sections on background and testing, advanced disease, therapeutics, and toxicity considerations.
  • Includes a timely section on innovative future therapies.

Author Information
By Sara Hurvitz, MD and Kelly McCann
More Information
ISBN Number 9780323581226
Description Author List By Sara Hurvitz, MD and Kelly McCann
Copyright Year 2019
Edition Number 1
Format Book
Trim 191w x 235h (7.50" x 9.25")
Imprint Elsevier
Page Count 250
Publication Date 16 Aug 2018
Stock Status Please allow 10-14 working days for delivery

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Background/testing

1. The HER2 alteration in breast cancer

2. HER2 testing in the era of changing guidelines

Advanced Disease

3. Optimal first-line treatment of HER2+ advanced disease

4. Second line therapy and beyond

5. HER2+ CNS metastases

Therapeutics

6. Neoadjuvant therapy

7. Adjuvant therapy

8. Outcomes based on HR status in early stage disease

9. De-escalation of therapy for small tumor

Toxicity considerations

10. Cardiac toxicity of HER2-targeted regimens

11. Non-cardiac toxicity of HER2-targeted therapy

Therapies on the horizon

12. Targeting other pathways active in HER2+ disease (CDK4/6, VEGF, PI3K, mTOR, FGFR, PARP, antibody-drug conjugates, etc)

13. Harnessing the immune system in HER2+ disease

14. Biosimilars

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