The new edition of this well-known text is an introduction to general pathology: a subject that bridges the divide between the basic biological sciences and the practice of clinical medicine. The functional and structural changes that occur in cells and tissues as a result of direct damage by, or reactions to, a wide variety of unfavourable circumstances are described. Full account is taken of the rapidly increasing understanding of the underlying molecular mechanisms.
Key Features
Improved illustrationsMore on molecular mechanisms
Author Information
By Katherine Woolf, PhD FHEA, Lecturer in Medical Education, UCL Division of Medical Education, London, UK
The nature of pathology
Cell injury and its manifestations
Cell and tissue death
Acute inflammation I: introduction
Acute inflammation II: cellular events and chemical mediators
Factors that modify the immune response
The natural history of acute inflammation I: healing
The natural history of acute inflammation II: wound healing
The natural history of acute inflammation III: chronicity
The immune system
Disorders related to the immune system
Autoimmune disease
Transplantation and the major histocompatability complex
Granulomatous inflammation
Some specific granulomatous disorders
Amyloid and amyloidosis
General pathology of viral infections
Atherosclerosis
Thrombosis
Embolism
Ischaemia and infarction
Abnormal accumulation of fluid and disorders of blood distribution
Pigmentation and heterotropic calcification
Neoplasia: disorders of cell proliferation and differentiation
Non-neoplastic disturbance in cell growth and proliferation
Cell proliferation and differentiation in relation to neoplasia
Relationship of neoplastic cells with their environment: tumour spread
Effects of neoplasms on the host
Effect of the host on neoplasms
Oncogenesis and the molecular biology of cancer
Oncogenesis
Genetic disorders
Single gene defects