Edited by Ross E. Petty, MD, PhD, DSc (Hon), FRCPC, Ronald M. Laxer, MDCM, FRCPC, Lucy Wedderburn, MD, MA, PhD, FRCP, Elizabeth D. Mellins, MD, Robert C. Fuhlbrigge, MD PhD, Jonathan Akikusa, MD and Hermine Brunner, MD, MSc, MBA
This core textbook discusses the presentation and pathophysiology, differential diagnosis, management, and prognosis for a comprehensive range of pediatric rheumatic conditions. Global leaders in the field provide evidence-based guidance highlighted
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This core textbook discusses the presentation and pathophysiology, differential diagnosis, management, and prognosis for a comprehensive range of pediatric rheumatic conditions. Global leaders in the field provide evidence-based guidance highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies the investigation, recognition, and management of rheumatic diseases in childhood and adolescence.
This core textbook discusses the presentation and pathophysiology, differential diagnosis, management, and prognosis for a comprehensive range of pediatric rheumatic conditions. Global leaders in the field provide evidence-based guidance highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies the investigation, recognition, and management of rheumatic diseases in childhood and adolescence.
Key Features
Addresses the full spectrum of rheumatic diseases, from typical juvenile idiopathic arthritis to rare and newly recognized syndromes, providing practical guidance on diagnosis, outcome measurement, and management—including both pharmacologic and multidisciplinary strategies
Covers state-of-the-art advances in pediatric rheumatology, including genomic and multi-omics approaches, the latest targeted therapies, modern imaging, and evolving concepts in autoinflammation and immune deficiency
Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible, and provides updates of laboratory investigations, imaging techniques, physical and occupational therapy, approach to chronic musculoskeletal pain syndromes, and much more
Features reviews of the complex symptoms, signs, and laboratory abnormalities that characterize these disorders
Shares the knowledge and expertise of two new editors, Drs. Jonathan Akikusa and Hermine Brunner, and 38 new contributing authors who are international leaders in the field of pediatric rheumatology
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
Author Information
Edited by Ross E. Petty, MD, PhD, DSc (Hon), FRCPC, Professor Emeritus, Pediatric Rheumatology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada; Ronald M. Laxer, MDCM, FRCPC, Professor, Departments of Pediatrics and Medicine, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada; Lucy Wedderburn, MD, MA, PhD, FRCP, Professor in Paediatric Rheumatology, Institute of Child Health, University College London; Consultant in Paediatric Rheumatology, Department of RheumatologyGreat Ormond Street Hospital National Health Service Trust, London, UK; Elizabeth D. Mellins, MD, Professor of Pediatrics, Department of Pediatrics – Human Gene Therapy, Stanford University, Stanford, California, USA; Robert C. Fuhlbrigge, MD PhD, Professor and Section Head – Pediatric Rheumatology, University of Colorado; Children’s Hospital Colorado, Aurora, Colorado, USA; Jonathan Akikusa, MD, Pediatric Rheumatology and Head of Unit, The Royal Children’s Hospital Melbourne, Melbourne, Australia; Hermine Brunner, MD, MSc, MBA, Director, Division of Rheumatology and Professor, UC Department of Pediatrics, Cincinnati Children's Hospital, USA
Edited by Ross E. Petty, MD, PhD, DSc (Hon), FRCPC, Professor Emeritus, Pediatric Rheumatology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada; Ronald M. Laxer, MDCM, FRCPC, Professor, Departments of Pediatrics and Medicine, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada; Lucy Wedderburn, MD, MA, PhD, FRCP, Professor in Paediatric Rheumatology, Institute of Child Health, University College London; Consultant in Paediatric Rheumatology, Department of RheumatologyGreat Ormond Street Hospital National Health Service Trust, London, UK; Elizabeth D. Mellins, MD, Professor of Pediatrics, Department of Pediatrics – Human Gene Therapy, Stanford University, Stanford, California, USA; Robert C. Fuhlbrigge, MD PhD, Professor and Section Head – Pediatric Rheumatology, University of Colorado; Children’s Hospital Colorado, Aurora, Colorado, USA; Jonathan Akikusa, MD, Pediatric Rheumatology and Head of Unit, The Royal Children’s Hospital Melbourne, Melbourne, Australia; Hermine Brunner, MD, MSc, MBA, Director, Division of Rheumatology and Professor, UC Department of Pediatrics, Cincinnati Children's Hospital, USA
Section 1. Introduction 1. Evolution of Pediatric Rheumatology
Section 2: Basic Concepts 2. Structure and Function 3. Innate Immunity 4. Adaptive Immunity 5. Multi-omics Approaches to Rheumatic Disease 6. Genetics and Pediatric Rheumatic Diseases
Section 3: Clinical Research in Pediatric Rheumatology 7. Understanding Clinical Investigations 8. Clinical Outcome Measures in Pediatric Rheumatic Diseases
Section 4: Clinical Investigations in Pediatric Rheumatology 9. Laboratory Investigations 10. Imaging in Pediatric Rheumatic Diseases
Section 5: Management of Rheumatic Diseases in Children 11. Principles in the Management of Patients with Rheumatic Diseases 12. Therapeutics: Nonbiologics 13. Therapeutics: Biologics and Targeted Small Molecules 14. Physical and Occupational Therapy 15. The Assessment and Management of Osteoporosis in Childhood
Section 7 Arthritis Related to Infection 23. Acute Rheumatic Fever and Post-Streptococcal Arthritis 24. Reactive Arthritis 25. Lyme Disease 26. Infectious Arthritis and Osteomyelitis
Section 8: Autoimmune and Inflammatory Connective Tissue Disorders and Related Syndromes 27. Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, and Undifferentiated Connective Tissue Disease 28. Neonatal Lupus Erythematosus 29. Antiphospholipid Syndrome 30. Juvenile Dermatomyositis and Other Inflammatory Muscle Diseases 31. Juvenile Systemic Sclerosis 32. Localized Scleroderma and Eosinophilic Fasciitis 33. Sjögren Disease and Immunoglobulin-G4 Related Disease 34. Raynaud Phenomena and Vasomotor Syndromes 35. Inflammatory Central Nervous System Disorders
Section 9: Vasculitis 36. Vasculitis and Its Classification 37. Takayasu Arteritis 38. Polyarteritis Nodosa 39. Kawasaki Disease 40. Antineutrophil Cytoplasmic Antibody Associated Vasculitis 41. Immune Complex Small-Vessel Vasculitis: IgA Vasculitis and Hypersensitivity Vasculitis 42. Behcet Syndrome and its Mimics 43. Central Nervous System Vasculitis 44. Other Vasculitides
Section 10:Immune System Dysfunction, Autoinflammation and Immune Deficiency 45. Periodic Fever Syndromes and Other Inherited Autoinflammatory Diseases 46. Autoinflammatory Bone Diseases 47. Blau Syndrome, Sarcoidosis and Related Systemic Granulomatous Diseases 48. Macrophage Activation Syndrome 49. Inborn Errors of Immunity and Rheumatic Diseases
Section 11. Musculoskeletal Manifestations of Systemic Disorders 50. Malignancies and Non-malignant Musculoskeletal Conditions That May Mimic Rheumatic Disease 51. Musculoskeletal Manifestations of Inflammatory Bowel Disease 52. Musculoskeletal Manifestations of Systemic Disease
Section 12. Non-Inflammatory Musculoskeletal Conditions and Pain Syndromes 53. Primary Disorders of Connective Tissue 54. Localized Musculoskeletal Pain 55. Primary and Secondary Chronic Musculoskeletal Pain Syndromes
https://www.elsevierhealth.com.au/textbook-of-pediatric-rheumatology-9780443119804.html332091Textbook of Pediatric Rheumatologyhttps://secure-ecsd.elsevier.com/covers/80/Tango2/large/9780443119804.jpg223.27405.94AUDInStock/Medicine/Clinical/General Medicine/Medicine/Rheumatology/Product Format/Book/Medicine/Clinical/General Medicine/Medicine/Rheumatology/Product Format/Book/Books/Japan Titles/Medicine & Surgery/Clinical/General Medicine/Medicine & Surgery/Rheumatology/Product Format/Book5259874525983559368295054591505455559368245255039526316043351024335090593681015145120525983352598735936828488653650545535936823418269243350885936809This core textbook discusses the <b>presentation and pathophysiology, differential diagnosis, management, and prognosis</b> for a comprehensive range of pediatric rheumatic conditions. Global leaders in the field provide <b>evidence-based guidance highlighted by superb full-color illustrations</b> that facilitate a thorough understanding of the science that underlies the investigation, recognition, and management of rheumatic diseases in childhood and adolescence. This core textbook discusses the <b>presentation and pathophysiology, differential diagnosis, management, and prognosis</b> for a comprehensive range of pediatric rheumatic conditions. Global leaders in the field provide <b>evidence-based guidance highlighted by superb full-color illustrations</b> that facilitate a thorough understanding of the science that underlies the investigation, recognition, and management of rheumatic diseases in childhood and adolescence.00add-to-cart97804431198042026ProfessionalEdited by Ross E. Petty, MD, PhD, DSc (Hon), FRCPC, Ronald M. Laxer, MDCM, FRCPC, Lucy Wedderburn, MD, MA, PhD, FRCP, Elizabeth D. Mellins, MD, Robert C. Fuhlbrigge, MD PhD, Jonathan Akikusa, MD and Hermine Brunner, MD, MSc, MBA20279Book216w x 276h (8.50" x 10.875")Elsevier76024 Apr 2026Available for Pre-OrderEdited by <STRONG>Ross E. Petty</STRONG>, MD, PhD, DSc (Hon), FRCPC, Professor Emeritus, Pediatric Rheumatology, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada; <STRONG>Ronald M. Laxer</STRONG>, MDCM, FRCPC, Professor, Departments of Pediatrics and Medicine, University of Toronto; Division of Rheumatology, The Hospital for Sick Children, Toronto, Ontario, Canada; <STRONG>Lucy Wedderburn</STRONG>, MD, MA, PhD, FRCP, Professor in Paediatric Rheumatology, Institute of Child Health, University College London; Consultant in Paediatric Rheumatology, Department of RheumatologyGreat Ormond Street Hospital National Health Service Trust, London, UK; <STRONG>Elizabeth D. Mellins</STRONG>, MD, Professor of Pediatrics, Department of Pediatrics – Human Gene Therapy, Stanford University, Stanford, California, USA; <STRONG>Robert C. Fuhlbrigge</STRONG>, MD PhD, Professor and Section Head – Pediatric Rheumatology, University of Colorado; Children’s Hospital Colorado, Aurora, Colorado, USA; <STRONG>Jonathan Akikusa</STRONG>, MD, Pediatric Rheumatology and Head of Unit, The Royal Children’s Hospital Melbourne, Melbourne, Australia; <STRONG>Hermine Brunner</STRONG>, MD, MSc, MBA, Director, Division of Rheumatology and Professor, UC Department of Pediatrics, Cincinnati Children's Hospital, USABooksBookUnited StatesNoNoNoNoNoPlease SelectPlease SelectNoNoPlease Select
