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McAlpine's Multiple Sclerosis, 5th Edition

Author :
By Alasdair Coles, PhD, Alastair Compston, PhD, MBBS, FRCP, V. Wee Yong, Catherine Lubetzki, Hans Lassmann, Brian Weinshenker, Steve Vucic, Benjamin M. Jacobs, PhD BM BCh (Oxon), Maria A. Rocca and Ruth Dobson
This item will be released on 24-07-2026
For more than 70 years, McAlpine's Multiple Sclerosis has been the gold standard textbook on the science and clinical practice of MS. The 5th Edition of this classic, landmark text reflects recent advances in this complex field, bringing you up to da ...view more
For more than 70 years, McAlpine's Multiple Sclerosis has been the gold standard textbook on the science and clinical practice of MS. The 5th Edition of this classic, landmark text reflects recent advances in this complex field, bringing you up to date with current information on genetics, epidemiology, clinical neurology, pathogenesis, and management of this common neurological disease. Easy to read and abundantly illustrated, this updated reference is a must-have resource for neurologists, neuropathologists, neurophysiologists, researchers, PM&R specialists, and others who can benefit from authoritative, comprehensive coverage of both scientific and clinical aspects of MS.
ISBN :
9780323936347
Publication Date :
24-07-2026
Stock Status :
Available for Pre-Order
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For more than 70 years, McAlpine's Multiple Sclerosis has been the gold standard textbook on the science and clinical practice of MS. The 5th Edition of this classic, landmark text reflects recent advances in this complex field, bringing you up to date with current information on genetics, epidemiology, clinical neurology, pathogenesis, and management of this common neurological disease. Easy to read and abundantly illustrated, this updated reference is a must-have resource for neurologists, neuropathologists, neurophysiologists, researchers, PM&R specialists, and others who can benefit from authoritative, comprehensive coverage of both scientific and clinical aspects of MS.

Key Features
  • Discusses recent advances in both diagnosis and management, including improved understanding of MS in childhood and the elderly, anti-MOG disease, treatments of progressive MS, remyelination and neuroprotective therapies, and more
  • Offers authoritative reviews of the current literature, placed in historical context
  • Features more than 550 high-quality illustrations clarifying important scientific and clinical concepts
  • Provides the most authoritative and comprehensive history of the understanding of the disease
  • Uses a remarkably clear presentation to make complicated data easier to understand
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

Author Information
By Alasdair Coles, PhD, Professor, Neuroimmunology, University of Cambridge, Cambridge UK; Alastair Compston, PhD, MBBS, FRCP, Professor of Neurology, University of Cambridge, Cambridge, UK; V. Wee Yong, Professor of Translational Neuroscience, Hotchkiss Brain Institute and the Departments of Clinical Neurosciences and Oncology at The University of Calgary, Canada; Catherine Lubetzki, Professor of Neurology, Pierre and Marie Curie University, head, Department of Neurological Diseases, Salpêtrière Hospital, France; Hans Lassmann; Brian Weinshenker, Professor of Neurology, University of Virginia, USA; Steve Vucic; Benjamin M. Jacobs, PhD BM BCh (Oxon); Maria A. Rocca, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Italy and Ruth Dobson, MBBS, PhD
More Information
ISBN Number 9780323936347
Description Author List By Alasdair Coles, PhD, Professor, Neuroimmunology, University of Cambridge, Cambridge UK; Alastair Compston, PhD, MBBS, FRCP, Professor of Neurology, University of Cambridge, Cambridge, UK; V. Wee Yong, Professor of Translational Neuroscience, Hotchkiss Brain Institute and the Departments of Clinical Neurosciences and Oncology at The University of Calgary, Canada; Catherine Lubetzki, Professor of Neurology, Pierre and Marie Curie University, head, Department of Neurological Diseases, Salpêtrière Hospital, France; Hans Lassmann; Brian Weinshenker, Professor of Neurology, University of Virginia, USA; Steve Vucic; Benjamin M. Jacobs, PhD BM BCh (Oxon); Maria A. Rocca, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Italy and Ruth Dobson, MBBS, PhD
Copyright Year 2027
Edition Number 5
Format Book
Trim 216w x 276h (8.50" x 10.875")
Imprint Elsevier
Page Count 980
Publication Date 24 Jul 2026
Stock Status Available for Pre-Order

1. The story and iconography of MS
The story of MS

2. The course and cost of MS
The distribution of MS
The natural history of MS

3. Definition of progressive MS
The impact of MS on the individual and society

4. Health economics of MS and its treatment
Endpiece

5. The clinical features and diagnosis of MS
The symptoms and signs of MS

6. The prodrome of MS

7. MS in children and the elderly
The diagnosis of MS

8. Assessment of the eye in MS
The prognosis of MS
The differential diagnosis of MS

9. Neuromyelitis opcitca and anti-MOG disease
Endpiece

10. The pathogenesis of MS
The genetics of MS
The immunology of MS
The neurobiology of MS
The pathophysiology of MS
The pathology of MS
Endpiece

11. The treatment of MS
Care of the person with MS

12. Models of care for the patient with MS
Treatment of symptoms of MS
Strategies for disease modification in MS

13. Monitoring the treatment of MS
Immunological therapies in MS
Reparative therapies in MS
Endpiece

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