The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application.
the course of malignancy and design appropriate treatment protocols byunderstanding the scientific underpinnings of cancer.
Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures.
Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy.
New to this Edition
Stay current with the latest discoveries in molecular and genomic research.
Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology.
Access the entire text and illustrations online, fully searchable, at Expert Consult.
16. Stromal-Cancer Interactions in the Microenvironment
17. Hypoxia and Angiogenesis
18. Invasion and Metastasis
19. Inflammation and Cancer
20. Molecular Pathways and Systems Biology
Part III: Molecular Pathology and Diagnostics
21. Biomarkers Assessing Risk of Cancer
22. Biomarkers for Detecting Cancer: Molecular Screening
23. Biomarkers for Predicting Response to Specific Therapy
24. The Technology of Analyzing Nucleic Acids
25. Imaging Cancer
By John Mendelsohn, MD, Professor, Department of Experimental Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas
; Peter M. Howley, MD, Shattuck Professor of Pathological Anatomy, Department of Microbiology and Immunobiology, Division of Immunology, Harvard Medical School, Boston, Massachusetts
; Mark A. Israel, MD, Director, Norris Cotton Cancer Center, Professor of Pediatrics and Genetics, Dartmouth Medical School, Hanover, New Hampshire; Joe W. Gray, PhD, Gordon Moore Professor and Chair, Biomedical Engineering, Oregon Health and Science University (OHSU) Director, OHSU Center for Spatial Systems Biomedicine, Portland, Oregon; Emeritus Professor, UCSF, and Visiting Faculty, Lawrence Berkeley National Laboratory, Berkeley, California
and Craig B. Thompson, MD, President and CEO, Memorial Sloan-Kettering Cancer Center, New York, New York
276 x 216 (8 1/2 x 10 7/8)
Please allow 3 - 4 weeks for delivery.
"This is a well-organized and well-written book that improves readers' understanding of the diverse mechanisms involved in cancer risk, growth, and treatments. The book provides a unique experience, uniting basic science with clinical applications to provide an integrated appreciation of the diverse molecular biology of cancer. It should be in the library of anyone interested in cancer research and treatment."-Karen L Reckamp, MD, MS(City of Hope) Doody Review: 4 stars