From the experts at Johns Hopkins University who bring you the bestselling Harriet Lane Handbook, the Harriet Lane Handbook of Pediatric Antimicrobial Therapy delivers quick, dependable answers to help you effectively treat a broad spectrum of pediatric infectious diseases. This highly regarded medical reference book is your pocket-sized source for all of the evidence-based recommendations you need to provide the best possible care to your young patients.
Get all of the information you need to prescribe the correct drug and the appropriate dose
through a detailed drug formulary, expanded from the popular Harriet Lane Handbook.
Better manage persistent, hard-to-fight pediatric infections with a section on adverse effects and drug resistance.
New to this Edition
Make the best clinical decisions
with up-to-date practice guidelinesfrom the AAP, CDC, and other authoritative pediatric and infectious disease sources.
Stay on top of the most effective treatments with leading-edge coverage of antiretroviral drugs for HIV and hepatitis; antimicrobial pharmacokinetic/pharmacodynamics (PK/PD) information; the latest Vancomycin therapeutic drug-monitoring recommendations; antimicrobial desensitization; pediatric developmental effects of antimicrobials approved in adults but not children; and much more.
Depend on the professional wisdom of an expert author team, combined with the front-line input of currentpediatric infectious disease fellows.
Access the fully searchable text online at Expert Consult.
II. Recommended Treatment forMycobacterial Infections
III. Recommended Treatment forViral Infections
IV. Recommended Treatment forFungal Infections
V. Recommended Treatment for Parasitic and Protozoal Infections
2. Recommended Empiric Antimicrobial Therapy for Selected Clinical Syndromes
3. Drug Dosing in Special Circumstances
4. Mechanisms of Action and Routes of Administration of Antimicrobial Agents
5. Mechanisms of Drug Resistance
I. Common Mechanisms of Microbial Resistance
II. Discordance Between in Vitro Susceptibility and in Vivo Efficacy
6. Therapeutic Drug Monitoring
I. General Principles
II. Antimicrobials Requiring Therapeutic Drug Monitoring
III. Special Topics in Antimicrobial Therapeutic Drug Monitoring
IV. Pharmacokinetic Monitoring in Therapeutic Drug Monitoring
V. Pharmacokinetic/Pharmacodynamic (PK/PD) Antimicrobial Relationships
VI. Drug Interactions
7. Adverse Drug Reactions
III. Central Nervous System
8. Recommended Antimicrobial Prophylaxis for Selected Infectious Agents and Conditions
9. Antimicrobial Desensitization Protocols
IV. Trimethoprim/Sulfamethoxazole (TMP/SMX) Oral
By Julia McMillan, MD, Director, Residency Program, Vice Chair for Pediatric Education, Professor, Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD; Carlton K. Lee, PharmD, MPH, Assistant Professor and Clinical Coordinator, Pediatrics, Department of Pharmacy, Johns Hopkins Hospital, Baltimor, MD; George K. Siberry, MD, MHP, Co-Chair, Infection Control, Krieger Institute, Assistant Professor of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD and Karen Carroll, MD
187 x 111 (4 3/8 x 7 3/8)
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"This is a wonderful reference for prescribing antibiotics for pediatric patients. It not only matches the bug with a drug, it also addresses various prescribing concerns that are important to safely and effectively dose and monitor patients. This second edition has revised and updated mechanisms of action, resistance, and empiric therapy sections as well as revised dosing in special circumstances, therapeutic monitoring, adverse drug reactions, and antimicrobial desensitization protocols. Current available evidence and guidelines were reviewed to provide the recommendations in this book. Because guidelines change, antibiotic resistance surfaces, and new information emerges, this new edition is warranted."-Judith Klevan, BSPharm(Jeanes Hospital) Doody Review: 4 stars