This book covers the core of both basic science and clinical immunology as required by medical students. Immunology is an inherently difficult subject and most competing titles include far too much complex scientific detail for most medical courses. This book covers just the core of the subject essential for understanding the clinical importance of the immune system and diseases caused by its malfunction.
Basic Immunology Introduction and Natural Immunity Defence Mechanisms (1) Defence Mechanisms (2) Phagocytosis Complement The Acute-phase Response/Interferon Mast Cells and Inflammation/Natural Killer Cells Tutorial 1 Adaptive Immunity - Lymphocytes The Lymphocyte and Lymphoid Tissue B and T Lymphocytes The Mucosal Immune System Recognition Molecules Self versus Non-Self Discrimination Antibody Tutorial 2 Adaptive Immunity - The Immune Response Lymphocyte Activation and Clonal Selection Adaptive Responses ñ Antibody Adaptive Responses ñ T Cells and Cell-mediated Immunity Cytokines Disposal Mechanisms ñ Cytotoxicity Immunity to Infection ñ Host Defence Mechanisms Immunity to Infection ñ Parasite Escape Mechanisms Tutorial 3 Immunopathology Acute and Chronic Inflammation Hypersensitivity Autoimmunity Infectious Disease Transplant Rejection Immunodeficiency Tutorial 4 Clinical Immunology Immunology in Medicine Respiratory Disease The Gut and Liver Endocrine Disease Renal Disease The Eye and Nervous System Skin Disease Connective Tissue Diseases (1) Connective Tissue Diseases (2) Blood Diseases Infectious Diseases Vaccination Acquired immunodeficiency Syndrome (AIDS) Clinical Aspects of HLA Malignant Disease Drugs and the Immune System Tutorial 5 Investigating the Immune System Immunodeficiency/Tumours of the Immune System Allergy and Autoimmunity/The Transplant Patient
Appendices The Language of Immunology Some Useful Abbreviations Cluster of Differentiation (CD) Antigens Changes in Circulating Lymphocytes Populations and Serum Immunoglobulin Levels with Age
By J. H. L. Playfair, MB, BChir, PhD, DSc, Professor Emeritus, Department of immunology, University College London Medical School, London; and P. M. Lydyard, BSc, MSc, PhD, FRCPath, Professor, Department of Immunology, Univesity College London Medical School, London