Hematology, 6th Edition encompasses all of the latest scientific knowledge and clinical solutions in the field, equipping you with the expert answers you need to offer your patients the best possible outcomes. Ronald Hoffman, MD, Edward J. Benz, Jr., MD, Leslie E. Silberstein, MD, Helen Heslop, MD, Jeffrey Weitz, MD, John Anastasi, MD, and a host of world-class contributors present the expert, evidence-based guidance you need to make optimal use of the newest diagnostic and therapeutic options.
Make confident, effective clinical decisions
by consulting the world's most trusted hematology reference.
Access the complete contents online at www.expertconsult.com, with a downloadable image collection, regular updates, case studies, patient information sheets, and more.
New to this Edition
Apply all the latest knowledge
on regulation of gene expression, transcription splicing, and RNA metabolism; pediatric transfusion therapy; principles of cell-based gene therapy; allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia and myelodysplastic syndrome in adults; hematology in aging; and much more, thanks to 27 brand-new chapters plus sweeping updates throughout.
Find the information you need quickly and easily thanks to a completely reworked organization that better reflects today's clinical practice.
Visualize clinical problems more clearly with new and updated images that reflect the pivotal role of hematopathology in modern practice.
Benefit from the experience and fresh perspective of new editor Dr. Jeffrey Weitz, Professor of Medicine at McMaster University School of Medicine and Executive Director of the Thrombosis and Atherosclerosis Research Institute in Ontario.
108 Unrelated Donor Cord Blood Transplantation for Hematologic Malignancies
109 Graft-versus-Host Disease and Graft-versus-Leukemia Responses
110 Complications After Hematopoietic Stem Cell Transplantation
PART XI: Transfusion Medicine
111 Human Blood Group Antigens and Antibodies
112 Principles of Red Blood Cell Transfusion
113 Principles of Platelet Transfusion Therapy
114 Human Leukocyte Antigen and Human Neutrophil Antigen Systems
115 Principles of Neutrophil (Granulocyte) Transfusions
116 Principles of Plasma Transfusion: Plasma, Cryoprecipitate, Albumin, and Immunoglobulins
117 Preparation of Plasma-Derived and Recombinant Human Plasma Proteins
118 Transfusion Therapy for Coagulation Factor Deficiencies
120 Transfusion Reactions to Blood and Cell Therapy Products
121 Transfusion-Transmitted Diseases
122 Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ Transplantation
123 Pediatric Transfusion Medicine
PART XII: Hemostasis and Thrombosis
124 Overview of Hemostasis and Thrombosis
125 The Blood Vessel Wall
126 Megakaryocyte and Platelet Structure
127 Molecular Basis for Platelet Function
128 Molecular Basis of Blood Coagulation
129 Regulatory Mechansims in Hemostasis
130 Clinical Approach to the Patient with Bleeding or Bruising
131 Laboratory Evaluation of Hemostatic and Thrombotic Disorders
132 Acquired Disorders of Platelet Function
133 Diseases of Platelet Number: Immune Thrombocytopenia, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura
134 Thrombocytopenia Caused by Platelet Destruction, Hypersplenism, or Hemodilution
135 Heparin-Induced Thrombocytopenia
136 Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome
137 Hemophilia A and B
138 Inhibitors in Hemophilia A and B
139 Rare Coagulation Factor Deficiencies
140 Structure, Biology, and Genetics of von Willebrand Factor
141 Disseminated Intravascular Coagulation
142 Hypercoagulable States
143 Antiphospholipid Syndrome
144 Venous Thromboembolism
145 Mechanical Interventions in Arterial and Venous Thrombosis
148 Acute Coronary Syndromes
149 Atrial Fibrillation
150 Peripheral Artery Disease
151 Antithrombotic Drugs
152 Disorders of Coagulation in the Neonate
PART XIII: Consultative Hematology
153 Hematologic Changes in Pregnancy
154 Hematologic Manifestations of Childhood Illness
155 Hematologic Manifestations of Liver Disease
156 Hematologic Manifestations of Systemic Disease: Renal Disease
157 Hematologic Manifestations of Cancer
158 Integrative Therapies in Patients with Hematologic Diseases
159 Hematologic Manifestations of HIV/AIDS
160 Hematologic Aspects of Parasitic Diseases
161 Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis
162 The Spleen and Its Disorders
163 Hematology in Aging
164 (Online Only) Resources For The Hematologist: Interpretive Comments and Selected Reference Values for Neonatal, Pediatric, and Adult Populations
By Ronald Hoffman, MD, Professor of Hematology and Medical Oncology, the Mount Sinai School of Medicine, New York, New York; Edward J. Benz, Jr., MD, President, Dana-Farber Cancer Institute; Richard and Susan Smith Professor of Medicine, Professor of Pediatrics, Professor of Pathology, Harvard Medical School, Boston, Massachusetts; Leslie E. Silberstein, MD, Professor of Pathology, HMS; Director, Joint Program in Transfusion Medicine; Children's Hospital Boston; Brigham and Women's Hospital; Dana-Farber Cancer Institute; Senior Investigator, IDI; Director, Center for Human Cell Therapy, IDI; Boston, Massachusetts; Helen Heslop, MD, Professor, Departments of Medicine and Pediatrics Section of Hematology-Oncology, Baylor College of Medicine; Dan L. Duncan Chair Director, Adult Stem Cell Transplant Program, The Methodist Hospital; Associate Director Clinical Research, Dan L. Duncan Cancer Center; Houston, Texas; Jeffrey Weitz, MD, Professor of Medicine,McMaster University School of Medicine; Executive Director of the Thrombosis and Atherosclerosis Research Institute; Canada Research Chair in Thrombosis; Hamilton, Ontario, Canada and John Anastasi, MD, Associate Professor; Assistant Director, Hematopathology; Medical Director, Flow Cytometry; Department of Pathology, The University of Chicago; Chicago, Illinois
276 x 216 (8 1/2 x 10 7/8)
Please allow 3 - 4 weeks for delivery.
"This outstanding book will be a great resource to hematologists in practice and in training all over the world. It is current and, with plans for continually supplementing the online version as more information becomes available, it will continue to be up to date."
-Kehinde Adekola, MBBS Northwestern University Feinberg School of Medicine
5 Star - Doody's Rating, March 2013
"There has been a significant improvement in general layout and visual appearence between the 5th and 6th editions. The book is now in full colour throughout, with numerous sections of added and useful information contained in blue and red coloured boxes...The entire text of the book, including downloadable images, is available online, and includes updates to the book - such as the recent addition of arsenic trioxide and ATRA as treatment for acute promyelocytic leukaemia...for the truly discerning haematologist, only th fullest detail will suffice, and only Hoffman's Hematology: Basic Principles and Practice will do."